MCSB: Mathematical, Computational and Systems Biology at UC Irvine

Name	Research Area
Andricioaei, Ioan	Interface of structural molecular biology and physical chemistry
Aphasizhev, Ruslan	Molecular biology of trypanosomes, mitochondrial RNA editing, mechanisms of template-independent nucleotide recognition and transfer
Arora, Kavita	Drosophila development, TGF-beta signal transduction, cell signaling
Baldi, Pierre	Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining / Large-Scale Data Analysis: Information Access & Management / Computational Biology / Bioinformatics / Systems Biology
Bardwell, Lee	Use of molecular biology, biochemistry, genetics, cell biology and math/computation to study fundamental questions of cell signaling and regulation
Botvinick, Elliot	The relationship between mechanical stresses on cells and molecular signaling, or cellular mechanotransduction. Investigation of the role of the glycocalix in the transduction of fluid shear stress at the wall of blood vessels, and is constructing an instrument to study the scale of mechanical induction of vascular inflammation.
Brody, Jim	Single molecule dynamics, bioinformatics, functional genomics, surface plasmon resonance
Bush, Robin	Molecular Evolution of Pathogens
Calof, Anne	Regulation of neurogenesis and neural differentiation
Chance, Frances	Sensory processing by cortical circuitry, computational modeling
Cho, Ken	Growth factor signaling and functional genomics in Xenopus and zebrafish, stem cell research and diabetes, Bioinformatics and functional genomics, Veterbrate embryology and growth factor signaling
Cocco, Melanie	NMR spectroscopy, DNA-binding proteins, membrane proteins, cancer
Collins, Philip	Nanomaterial Synthesis & Characterization, Nanocircuit Behaviors, Single Molecule Circuits
Dennin, Michael	Biological physics, Langmuir monolayers, Foams
Fowlkes, Charless	Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining Bio-Medical Informatics / Computational Biology
Frank, Steve	Evolutionary genetics, host-parasite interactions, development of mathematical, computational and conceptual models to study complex phenotypes
George, Steven C.	Physiological systems modeling, respiratory heat and mass transport, kinetics, computer simulation, tissue engineering
Gratton, Enrico	Design of new fluorescence instruments, protein dynamics, hydration of proteins, and I.R. spectroscopy of biological substances
Gross, Steve	Biophysics of molecular motors and intracellular transport
Guidotti, Patrick	Partial Differential Equations and Applied (Functional) Analysis
Hayes, Wayne	Large-Scale Data Analysis: Information Access & Management / Databases / Information Infrastructure / Bio-Medical Informatics / Computational Biology
Hertel, Klemens	Mechanisms of pre-mRNA splicing and the function of splicing enhancers in exon definition, Regulation of pre-mRNA splicing and human genetic diseases, The coupling of transcription and pre-mRNA splicing
Huang, Lan	Biological mass spectrometry/proteomics, ubiquitin-proteasome degradation pathways, protein complexes, posttranslational modifications, protein-protein interaction
Huang, Taosheng	Molecular basis of genetic diseases in humans
Jeon, Noo Li	Developing microfluidic devices for biological research (i.e., cell migration, axon guidance, axon regeneration, and stem cell differentiation)
Keyak, Joyce	Orthopaedic surgery, orthopaedic biomechanics, bone mechanics, finite element analysis, quantitative computed tomography, and prosthesis design
Kibler, Dennis	Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining / Bio-Medical Informatics / Computational Biology / Computational Analysis of Genomes / Gene Regulation / Motif Discovery / Gene Expression Clustering
Komarova, Natalia	Mathematical biology: modeling of cancer initiation and progression, dynamics of DNA transcription and repair, modeling of learning and evolution of language
Lander, Arthur	Systems biology of morphogenesis and pattern formation, proteoglycans, extracellular matrix, birth defects syndromes
Lanyi, Janos	Bacteriorhodopsin, spectroscopy, protein crystallography
Lathrop, Rick	Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining / Bio-Medical Informatics / Computational Biology / Protein Structure Prediction / Drug Discovery / Genetic Regulation
Long, Anthony	Quantitative and population genetics, genetic basis of quantitative variation for different phenotypes in different organisms, gene mapping and microarray analysis
Lowengrub, John	Microstructured Materials, Multiphase Flows, Crystal Growth, Nanostructure Patterning, Metallic Alloys, Tumor Growth, Tissue Engineering
Luecke, Hartmut "Hudel"	Protein crystallography, structure function studies, membrane proteins, bacteriorhodopsin, annexi, G protein-coupled receptors (GPCR), structure-based drug design
Luo, Ray	Computational Biology, Protein Structure, Protein Function
Marsh, Larry	Regulation of growth factor signaling in patterning, regeneration, and oncogenesis, Mechanisms of late onset neurodegeneration
Martens, Craig	Theoretical Chemistry, Chemical Physics
McHenry, Matthew	Biomechanics, Locomotion, Sensory Biology
Meyer, Joerg	Biomedical imaging, large-scale visualization, earthquake simulation, virtual reality
Mjolsness, Eric	Artificial Intelligence: Automated Reasoning / Machine Learning / Data Mining / Bio-Medical Informatics / Computational Biology / Systems Biology / Scientific Inference Systems / Mathematical Methods
Mukamel, Shaul	Theoretical studies of ultrafast dynamics and relaxation processes of large molecules, biological complexes, and semiconductors; Nonlinear ultrafast spectroscopy
Nenadic, Zoran	Adaptive biomedical signal processing, control algorithms for biomedical devices, brain-machine interfaces, modeling and analysis of biological neural networks
Nie, Qing	Computational Biology, Developmental and Cell Biology, Numerical Analsis, Interface Dynamics in Materials and Fluids, High-Performance Computing, Modeling and Simulation of Tissue Patterning, Systems Biology
Przulj, Natasha	Bio-Medical Informatics / Computational Biology Theory: Analysis of Algorithms and Data Structures
Putnam, Andrew	Cell and Tissue Engineering, Extracellular Matrix, Integrins, Signal Transduction, Cell Adhesion and Migration, Stem Cells, Bone, Smooth Muscle, Polymeric Biomaterials
Ranz, Jose	Structural evolutionary genomics and evolution of the expression network
Reed, Robert	Developmental genetics of Heliconius wing patterns
Ritz, Thorsten	Biological physics, magnetic sense of animals, quantum biology of photosynthesis
Schilling, Tom	Zebrafish development, pattern formation, morphogenesis
Sheu, Phillip C-Y	Database Systems, Object-Oriented Systems, Parallel Processing, Simulation, Interactive Multimedia Systems. Biomedical Database Management, Intranet/Internet Technologies
Solna, Knut	Applied mathematics, applied probablility, stochastic differential equations
Tan, Ming	Gene Expression and Pathogenesis in Chlamydia Trachomatis
Thornton, Kevin	Comparative genomics, Population Genetics, and statistical Genetics
Tobias, Douglas	Computational Chemistry, Biophysical Chemistry, Atmospheric Chemistry
Tromberg, Bruce	Lasers, near infrared spectroscopy, non-invasive diagnostics, photomedicine, biomedical optics, photodynamic therapy
Tsai, Sheryl	Biochemistry, Chemical Biology, Structural Biology, Microbiology
Venugopalan, Vasan	Biomedical laser applications, optical diffusion theory, photothermal and photomechanical phenomena
Wan, Frederic Y.M.	Applied Mathematics, Solid Mechanics, Resource Economics, Biomathematics
Warrior, Rahul	Drosophila development, regulation of nuclear position and migration, effects of proteoglycans in growth factor signaling, regulation of developmental gene expression.
Waterman, Marian	Regulation of gene expression by LEF/TCF - beta-catenin complexes
Weiss, Gregory	Bioorganic chemistry, chemical biology, protein engineering, molecular biology and biochemistry
Wodarz, Dominik	Mathematical and Computational Biology, Theoretical Biology, infectious diseases and the immune system, carcinogenesis & cancer treatment
Xie, Xiaohui	Computational Biology, Bioinformatics, Genomics, Neural Computation, and Machine Learning
Xin, Jack	Analysis and Modeling of Reaction-Diffusion-Advection Fronts, Stochastic Partial Differential Equations, Asymptotics and Computations, Multiscale Analysis of Partial Differential Equations and Applications, Mathematical Modeling in Speech and Hearing Sciences.
Yi, Tau-Mu	Systems biology, quantitative description of G-protein signaling, and the analysis of the robustness of biological networks
Yu, Clare	Biological physics, Intracellular transport, Disordered systems
Zhao, Hong-kai	The Level Set Method, Moving Interface and Free Boundary, Image Processing and Computer Graphics, Time Reversal and Wave Propagation, Domain Decomposition